I do all my illustrations with the laser mouse, I don't have to hold a pen that way, It would be very hard for me to hold the pen for as many hrs as I use a mouse. My hands are getting more crippled so holding things like that wouldn't work, I would be afraid but everyone says I don't know what I'm missing. I do know I miss my traditional drawing..I draw and paint sometimes for for a limited amount of time.
This new mouse I have takes little pressure and is very precise and my hand just rests right on it.
Maybe I can rig something up to hold the tablet pen?
I bought a used wacom 6 x 8 intuos 4 years ago and it still works great - I use it exclusively everyday.
I've gone through a few packs of nibs...but that's it.
) The pen is a thicker than a standard pencil, so that helps. I find that I can create MUCH faster - so the time actually spent applying pressure would probably be less. 
